Status:

TERMINATED

The Effect of Nighttime Dialysis on the Inflammation of Kidney Failure

Lead Sponsor:

Rockefeller University

Collaborating Sponsors:

The Rogosin Institute

Conditions:

End-Stage Renal Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study will determine whether a new form of home hemodialysis carried out at night during sleep reduces blood levels of hormone-like substances called cytokines that may cause fatigue and increase...

Detailed Description

Patients treated with conventional hemodialysis for at least 3 months and interested in learning home nocturnal hemodialysis will be screened in the Rockefeller Outpatient Research Center. If eligible...

Eligibility Criteria

Inclusion

  • Men and women at least age 18 who receive hemodialysis three times a week for at least 3 months and meet the criteria for home instruction in nocturnal dialysis -

Exclusion

  • No diabetes, any unstable clinical condition, chronic infection (including hepatitis, HIV), endocrine disorders or serious digestive problems, lipid-lowering medication , LDL cholesterol \<190 mg/dL and triglycerides less than 600 mg/dL, body mass index \<35, blood pressure \<160/100, hemoglobin \>10.0, no cholesterol-lowering medicine, able to change from Renagel (has lipid effects) to Phoslo for the duration of the study, cigarette smoking no more than half a pack per day

Key Trial Info

Start Date :

July 1 2002

Trial Type :

INTERVENTIONAL

End Date :

May 1 2006

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00234130

Start Date

July 1 2002

End Date

May 1 2006

Last Update

June 3 2009

Active Locations (1)

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1

Rockefeller University Hospital

New York, New York, United States, 10021