Status:

COMPLETED

Evaluation of the Efficacy and Safety of Risperidone Injections Given Once a Month to Adults With Schizophrenia or Schizoaffective Disorder

Lead Sponsor:

Janssen, LP

Conditions:

Schizophrenia

Psychotic Disorders

Eligibility:

All Genders

18-65 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to assess the effectiveness and safety of long-acting risperidone given as a once monthly injection to adult patients with schizophrenia or schizoaffective disorder.

Detailed Description

Risperidone, taken by mouth on a daily basis, has been an effective treatment for schizophrenia and schizoaffective disorder. Risperidone is also available in a long-acting injectable form so that pat...

Eligibility Criteria

Inclusion

  • Diagnosis of schizophrenia or schizoaffective disorder
  • stable with respect to disease symptoms and other medical conditions
  • stable on antipsychotic therapy with oral risperidone 2 to 6 milligrams per day for 8 weeks before study
  • if female, using birth control.

Exclusion

  • Hospitalized within 8 weeks of beginning the study
  • at risk to self or others
  • presence of liver or kidney damage
  • use of oral antipsychotic drugs other than risperidone within the past 8 weeks, of injected antipsychotics within the past 6 months, of long-acting risperidone in an earlier study, of investigational drugs within the past 30 days, or of electroconvulsive therapy within the past 12 months
  • pregnant or breast-feeding
  • if female, not using birth control
  • abusing drugs or alcohol.

Key Trial Info

Start Date :

May 1 2002

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2003

Estimated Enrollment :

86 Patients enrolled

Trial Details

Trial ID

NCT00236353

Start Date

May 1 2002

End Date

December 1 2003

Last Update

May 17 2011

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