Status:

COMPLETED

A Study of the Effects of Risperidone and Olanzapine on Blood Glucose (Sugar) in Patients With Schizophrenia or Schizoaffective Disorder

Lead Sponsor:

Janssen, LP

Conditions:

Schizophrenia

Diabetes Mellitus

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to assess and compare how risperidone and olanzapine, two antipsychotic medications, affect the regulation of glucose (sugar) in the body.

Detailed Description

The newer antipsychotic medications risperidone and olanzapine effectively treat schizophrenia and related disorders, and they may cause fewer side effects than the older antipsychotic drugs do. Howev...

Eligibility Criteria

Inclusion

  • Diagnosis of schizophrenia or related disorder
  • stable with respect to disease symptoms and other medical conditions
  • would benefit from this type of antipsychotic drug
  • if female, using birth control.

Exclusion

  • Patients who are delirious, bipolar, severely mentally retarded, or suicidal
  • psychiatric diagnosis of disease unrelated to schizophrenia
  • presence of stroke, brain tumor, Parkinson's Disease, or diseases that affect blood glucose control
  • history of diabetes
  • long or recent history of taking risperidone, olanzapine, quetiapine, clozapine, or investigational drugs
  • recent history of unstable thyroid function
  • if female, not using birth control
  • abusing drugs or alcohol.

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2003

Estimated Enrollment :

59 Patients enrolled

Trial Details

Trial ID

NCT00236379

End Date

August 1 2003

Last Update

May 17 2011

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