Status:

COMPLETED

Safety and Efficacy Study of the Investigational Drug Pagoclone, in the Treatment of Persistent Developmental Stuttering (PDS)

Lead Sponsor:

Pharmacology Research Institute

Conditions:

Persistent Developmental Stuttering

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

This is a research study of the investigational drug, Pagoclone, in the treatment of persistent developmental stuttering (PDS), which includes frequent repetitions or prolongations of sounds or syllab...

Eligibility Criteria

Inclusion

  • PDS defined as DSM-IV-TR criteria
  • Symptoms starting before age 8
  • Total overall score of 18-36 on the SSI-3
  • English speaking, with an 8th grade education
  • Able to understand and cooperate with study requirements with assistance
  • Not pregnant or breastfeeding
  • Able to provide consent

Exclusion

  • No diagnoses of other CNS/Mental health disorders in the last 6 months
  • No use of psychotropic medication or other medication for stuttering within 4 weeks prior to screening
  • No use of non-medicinal stuttering treatments for 5 months prior to the study
  • No use of illicit drugs or opiates of any kind

Key Trial Info

Start Date :

April 1 2005

Trial Type :

INTERVENTIONAL

End Date :

December 1 2006

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00239915

Start Date

April 1 2005

End Date

December 1 2006

Last Update

May 9 2012

Active Locations (1)

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Pharmacology Research Institute

Riverside, California, United States, 92506