Status:
TERMINATED
Study Comparing Acne in Patients Taking Oral Minocycline to Patients Taking Minocycline Plus Topical Tretinoin
Lead Sponsor:
Derm Research @ 888 Inc.
Collaborating Sponsors:
Stiefel, a GSK Company
Conditions:
Acne Vulgaris
Eligibility:
All Genders
Phase:
PHASE4
Brief Summary
The use of oral antibiotics alone to treat inflammatory acne provides little to no long term therapeutic benefit. Acne relapse rates can be reduced by using topical tretinoin 0.01% in conjunction wit...
Detailed Description
Although oral antibiotics have been the mainstay of treatment of inflammatory acne for 30 years, studies comparing their efficacy have little scientific value. Evidence-based dermatology proves minoc...
Eligibility Criteria
Inclusion
- Provision of written consent
- Either sex
- Any age
- Diagnosis of acne vulgaris with a minimum of 20 inflammatory acne lesions on the face.
Exclusion
- Known hypersensitivity to tetracyclines
- Use of any oral antibiotics in the previous 3 months
- Pregnancy, breast-feeding or lactating
- Inability or unwillingness to comply with the requirements of the protocol, or agree to the use of their data as determined by the investigator.
- Concomitant medical condition which, in the investigator's opinion, may confound the study results or interfere with study assessments or outcomes.
- Patients with severe acne on the chest, back or trunk.
Key Trial Info
Start Date :
August 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2006
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT00240513
Start Date
August 1 2004
End Date
December 1 2006
Last Update
February 24 2012
Active Locations (1)
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1
Derm Research @ 888 Inc
Vancouver, British Columbia, Canada, V5Z 3Y1