Status:
COMPLETED
MOTIV Study- Effect of Antidepressive Treatment by Escitalopram in Patients Undergoing Coronary Artery Bypass Grafting
Lead Sponsor:
Hopital Jean Minjoz
Collaborating Sponsors:
H. Lundbeck A/S
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
30+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine the effect of an antidepressive medication (Escitalopram), started preoperatively and given during 6 months, on 6-month and 1 year post-operative morbidity an...
Detailed Description
Depression is known to have an adverse effect on post-operative mortality and morbidity after coronary artery bypass grafting. Cardiac surgery is known to cause transient depression in patients. The p...
Eligibility Criteria
Inclusion
- Patients undergoing elective coronary artery bypass surgery
- \> 30 years old
Exclusion
- Contra-indication to antidepressive treatment
- Already treated by antidepressive treatment
- Concomitant cardiac surgery as valve replacement etc.
- Patients having anticoagulation therapy
- Pregnant women
- Hepatic insufficiency
Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2012
Estimated Enrollment :
368 Patients enrolled
Trial Details
Trial ID
NCT00243477
Start Date
January 1 2006
End Date
February 1 2012
Last Update
March 19 2012
Active Locations (1)
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1
Sidney Chocron
Besançon, Doubs, France, 25000