Status:
COMPLETED
Possible Relation of Toll-Like Receptors and Nitric Oxide to Chronic Lung Disease
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Lung Diseases
Eligibility:
All Genders
Up to 1 years
Brief Summary
The first objective of this study is to determine if increased expression of one or more members of the toll-like receptor (TLR) family of receptors that are found on inflammatory cells (present in th...
Detailed Description
BACKGROUND: This study will examine the role of two members in the family of transmembrane receptors, TLRs, found on leukocytes and other cells that are upregulated in response to endotoxin and other...
Eligibility Criteria
Inclusion
- Birth weight less than 1250 gm
- Requiring assisted ventilation
Exclusion
- Moribund condition
- Major pulmonary or cardiovascular associated anomaly
Key Trial Info
Start Date :
January 1 2002
Trial Type :
OBSERVATIONAL
End Date :
May 1 2006
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00245167
Start Date
January 1 2002
End Date
May 1 2006
Last Update
July 29 2016
Active Locations (2)
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1
Children's Mercy Hospital & Clinic
Kansas City, Missouri, United States, 64108
2
Children's Hospital and Regional Medical Center (Seattle)
Seattle, Washington, United States, 98195