Status:

COMPLETED

Adherence of Stalevo, Entacapone and Levodopa

Lead Sponsor:

South Glasgow University Hospitals NHS Trust

Conditions:

Parkinson's Disease

Eligibility:

All Genders

18-85 years

Brief Summary

To test if combining two antiparkinson drugs into a single tablet improves accuracy of medicine intake by the patient. To test if patients with Parkinson's disease who take medicines at regular time ...

Eligibility Criteria

Inclusion

  • Patients diagnosed with Parkinson's disease aged between 18 and 85 years fulfilling UK Brain Bank criteria.
  • Current levodopa therapy prescribed on a regular basis three or more times per day but requiring entacapone because of 'wearing off'
  • Able to manipulate electronic monitoring bottles and complete questionnaires

Exclusion

  • Current use of compliance aid such that study participation would be detrimental to patient's adherence
  • Pregnancy or breast feeding
  • Excess alcohol (over 21 units per week for women and 28 units for men)
  • Mini mental state examination of less than 26.
  • Severe depression (Geriatric depression score over 20)

Key Trial Info

Start Date :

April 1 2005

Trial Type :

OBSERVATIONAL

End Date :

July 1 2006

Estimated Enrollment :

14 Patients enrolled

Trial Details

Trial ID

NCT00245700

Start Date

April 1 2005

End Date

July 1 2006

Last Update

May 23 2008

Active Locations (1)

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1

Southern General Hospital

Glasgow, Scotland, United Kingdom, G51 4TF