Status:

COMPLETED

RSV Disease in the Elderly

Lead Sponsor:

National Institute of Allergy and Infectious Diseases (NIAID)

Conditions:

Respiratory Infections, Acute

Respiratory Syncytial Virus

Eligibility:

All Genders

21-99 years

Brief Summary

Respiratory syncytial virus (RSV) causes sickness and deaths in older people every winter. This study will investigate how aging affects the body's immune response (body's response to disease) to RSV....

Detailed Description

Respiratory infections account for significant excess morbidity and mortality among older people each winter. Influenza A virus and Respiratory Syncytial Virus (RSV) have emerged as two of the most im...

Eligibility Criteria

Inclusion

  • Prospective Cohort
  • Greater than or equal to 21 years of age
  • Able to provide written consent
  • Telephone contact available
  • Will reside in the Upstate New York area throughout the winter months
  • Hospital Cohort
  • Greater than or equal to 21 years of age
  • Able to provide written consent or legal guardian able to provide written consent
  • Telephone contact available
  • Symptoms of respiratory tract infection for less than or equal to 30 days duration. Symptoms can be all or any of the following: nasal congestion, cough, new or increased sputum or dyspnea, sore throat, with or without fever

Exclusion

  • Prospective Cohort
  • Known immunosuppressive condition including: HIV, active cancer currently receiving chemotherapy, hematological malignancy, autoimmune disorders.
  • Documented RSV infection in the previous year
  • Participation in previous RSV vaccine study
  • Hospital Cohort
  • Known immunosuppressive condition including: HIV, active cancer currently receiving chemotherapy, hematological malignancy, autoimmune disorders.
  • Symptoms of a respiratory infection for longer than 30 days.
  • Participation in prior RSV vaccine study

Key Trial Info

Start Date :

October 3 2005

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 28 2008

Estimated Enrollment :

1401 Patients enrolled

Trial Details

Trial ID

NCT00246480

Start Date

October 3 2005

End Date

May 28 2008

Last Update

February 4 2019

Active Locations (1)

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1

Rochester General Hospital

Rochester, New York, United States, 14621