Status:
COMPLETED
Pathophysiology and Clinical Relevance of Endotoxin Tolerance in Humans
Lead Sponsor:
Radboud University Medical Center
Conditions:
Endotoxemia
Eligibility:
MALE
18-35 years
Phase:
PHASE1
Brief Summary
A number of diseases lead to a so called systemic inflammatory response syndrome (SIRS). This excessive response is self-destructive and leads to major complications of the initial disease: dysfunctio...
Detailed Description
See protocol
Eligibility Criteria
Inclusion
- Healthy male volunteers
Exclusion
- drug-, nicotine-, alcohol abuses
- tendency towards fainting
- BMI \< 18 kg/m2
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2007
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00246714
Start Date
October 1 2005
End Date
December 1 2007
Last Update
April 15 2008
Active Locations (1)
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1
Radboud University Nijmegen Medical Center
Nijmegen, Gelderland, Netherlands, 6500HB