Status:
COMPLETED
Brain Networks Responsible for Self-Agency
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Brain
Eligibility:
All Genders
18-80 years
Brief Summary
This study will examine how people consider their actions to be under their own control or not. The term to describe this feeling of being in control of one's own actions is called "agency." The sense...
Detailed Description
OBJECTIVE: The purpose of this study is to identify structural brain regions, using a block design blood oxygenation level-dependent functional magnetic resonance imaging (BOLD-fMRI), which are diffe...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Subjects age 18 and older.
- Subjects must be right-hand dominant (For healthy controls).
- Patients diagnosed with a probable or definite functional movement disorder by an HMCS physician or diagnosed with complete or near-complete sensory neuropathy.
- Subjects willing to abstain from caffeine or alcohol for 48 hours prior to the fMRI scanning.
- EXCLUSION CRITERIA:
- Subjects with any abnormal findings on neurological exam.
- Subjects with a positive urine pregnancy test.
- Subjects who are pregnant.
- Subjects with any finding on the MRI safety questionnaire which prevents them from safely undergoing an MRI scan.
- Subjects with metallic dental fillings which are likely to cause MRI artifacts.
- Subjects with any history of brain tumor, stroke, head trauma or a vascular malformation as obtained by history or from imaging studies.
- Subjects with any history of a severe medical condition, such as cardiovascular disease, which would prevent them from lying flat for up to 120 minutes.
- Subjects without the capacity to give informed consent.
- Subjects with claustrophobia or other restrictions which prevent them from undergoing a scan in a confined space for up to 60 minutes.
- Patients with excessive movements at rest.
- Patients with symptom remission.
Exclusion
Key Trial Info
Start Date :
October 27 2005
Trial Type :
OBSERVATIONAL
End Date :
October 28 2008
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00246831
Start Date
October 27 2005
End Date
October 28 2008
Last Update
July 2 2017
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892