Status:

COMPLETED

Immunonutrition in Cardiac Surgery

Lead Sponsor:

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Conditions:

Thoracic Surgery

Cardiac Surgery

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

Effect of two preoperative oral immune-enhancing nutritional supplements in patients at high risk of infection after cardiac surgery: a randomized placebo-controlled study. Introduction: In our first...

Detailed Description

Objective To study the effect of two preoperative immune enhancing nutritional supplements compared with a control nutritional supplement in 'high risk' risk cardiac surgery patients Introduction: El...

Eligibility Criteria

Inclusion

  • Patients undergoing cardiac surgery with the use of cardiopulmonary bypass, who met one of the following criteria
  • age \>= 70 years
  • poor left ventricular function (ejection fraction \< 0.4)
  • mitral valve replacement

Exclusion

  • Age =\< 21 years
  • Pregnancy
  • Insulin dependent diabetes mellitus
  • Hepatic Cirrhosis
  • Known malignancy
  • Use of chemotherapy, NSAIDs (except ASA), or corticosteroids
  • Schizophrenia
  • Severe renal failure (creatinine clearance \< 25 mL/h) before study entrance
  • Patients with an organ transplantation in the past

Key Trial Info

Start Date :

July 1 1996

Trial Type :

INTERVENTIONAL

End Date :

December 1 1998

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00247793

Start Date

July 1 1996

End Date

December 1 1998

Last Update

November 2 2005

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Cardiopulmonary Surgery, Academic Medical Center

Amsterdam, North Holland, Netherlands, 1105 AZ