Status:
COMPLETED
A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.
Lead Sponsor:
VA Office of Research and Development
Conditions:
Orthostatic Hypotension
Spinal Cord Injuries
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The purpose of this study is to determine how blood pressure and blood flow are controlled during head-up tilt in a semi-upright position. In this investigation we are studying blood pressure and bloo...
Detailed Description
Individuals with tetraplegia lack normal sympathetic nervous system regulation of blood pressure and, therefore, relative hypotension is a common occurrence. This hypotension may be more pronounced wi...
Eligibility Criteria
Inclusion
- Duration of spinal cord injury (SCI) at least 1 year
- Level of SCI C4-8 and T6 and below
- matched non-SCI subjects
- Chronological age between 18-65 years
- Euhydration: Subjects will be instructed to avoid caffeine and alcohol and to maintain normal salt and water intake for several days prior to study.
Exclusion
- Known heart and/or blood vessel disease
- Dehydration
- High blood pressure
- Kidney disease
- Diabetes mellitus
- Prescribed ACE inhibitors
- Acute Infection
- Smoking
- Pregnancy
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2012
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00248807
Start Date
October 1 2005
End Date
April 1 2012
Last Update
February 25 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
VA Medical Center, Bronx
The Bronx, New York, United States, 10468