Status:
COMPLETED
The Therapeutic Workplace Initiation Study
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Cocaine-Related Disorders
Opioid-Related Disorders
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The primary purpose of the study is to determine if the central feature of the Therapeutic Workplace, the abstinence reinforcement contingency, is critical to initiate cocaine abstinence in injection ...
Detailed Description
Methods Setting and Materials This study was conducted at the Center for Learning and Health, a treatment-research unit at the Johns Hopkins Bayview Medical Center, Baltimore, MD. The therapeutic work...
Eligibility Criteria
Inclusion
- Baseline inclusion criteria:
- are at least 18 years of age
- are enrolled in methadone maintenance treatment in Baltimore
- provide a cocaine-positive urine sample at time of initial screening
- self-report cocaine use through intravenous route
- have visible evidence of intravenous drug use (i.e., track marks).
- Baseline exclusion criteria:
- report current suicidal ideation
- if the individual reports hallucinations
- have physical limitations (e.g., broken fingers) that prevent the subject from typing.
- Applicants reporting hallucinations are excluded because this is a characteristic of a psychiatric disorder that is likely to result in behaviors that could disrupt the workplace or functioning or limit their ability to provide informed consent.
- Main study inclusion criteria:
- have attended the workplace regularly during 4-week baseline periods
- are still in methadone maintenance treatment at the end of the 4-week baseline period
- have provided at least two urine samples that test positive for cocaine during the baseline period
- Individuals who are excluded from the main study will be allowed to complete their 8-week training program in the Therapeutic Workplace. They may also be invited to participate in other studies ongoing at the Center for Learning and Health where this research takes place.
Exclusion
Key Trial Info
Start Date :
April 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2004
Estimated Enrollment :
117 Patients enrolled
Trial Details
Trial ID
NCT00249470
Start Date
April 1 2003
End Date
October 1 2004
Last Update
December 27 2017
Active Locations (1)
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1
The Center for Learning and Health
Baltimore, Maryland, United States, 21224