Status:
WITHDRAWN
Colony-Stimulating Factor-1 (CSF-1) and Other Cytokines in Human Endometrial Carcinogenesis
Lead Sponsor:
University of New Mexico
Conditions:
Uterine Neoplasms
Endometrial Neoplasms
Eligibility:
FEMALE
Brief Summary
The purposes of this study are the following: 1. To further characterize and quantify both CSF-1 and colony-stimulating factor-1 receptor (CSF-1R) expression from additional tumor specimens, specific...
Detailed Description
These experiments, taken together, should critically determine if there is a role for the CSF-1/ c-fms autocrine, endocrine, or paracrine loop in the progression of endometrial adenocarcinoma. If so, ...
Eligibility Criteria
Inclusion
- All patients undergoing hysterectomy, or who have endometrial cancer, and are under routine surveillance.
- Patients may have received prior hormonal, cytotoxic chemotherapy, irradiation or surgical therapy.
- Healthy post-menopausal and peri-menopausal women.
- A consent form must be signed by the patient prior to study entry.
Exclusion
- Patients who do not have primary uterine corpus tumors.
- Patients with less than one gram of tumor tissue available to procurement.
Key Trial Info
Start Date :
January 1 1998
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00250770
Start Date
January 1 1998
Last Update
July 5 2023
Active Locations (1)
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1
University of New Mexico
Albuquerque, New Mexico, United States, 87131