Status:
COMPLETED
Therapeutic Zinc in Childhood Pneumonia
Lead Sponsor:
Centre For International Health
Collaborating Sponsors:
Tribhuvan University, Nepal
Statens Serum Institut
Conditions:
Pneumonia
Eligibility:
All Genders
2-35 years
Phase:
PHASE2
PHASE3
Brief Summary
The aim of this study is to assess whether zinc given as adjuvant therapy to standard antibiotic treatment in children hospitalized for severe pneumonia reduces the duration of the severe illness and ...
Detailed Description
Nepal has an under-five mortality rate of 91/1000 live births. Pneumonia, one of the major killers accounts for the death of 25,000 - 35,000 Nepalese children every year. It is estimated that, on an a...
Eligibility Criteria
Inclusion
- Children aged 2- 35 months with a history of cough (duration \<14days) and difficult breathing of \</= 72hours' duration, with lower chest indrawing.
- Availability of informed consent.
Exclusion
- Children with severe wasting (\<70% NCHS median weight for height)
- Severe anemia (hemoglobin \<7 gm/dl.)
- Presence of heart disease with or without signs of cardiac failure.
- Child with a chronic cough (lasting for ≥14 days)
- Documented tuberculosis with ongoing treatment.
- Associated other severe diseases that require special care or surgical intervention.
- Children with concomitant diarrhea with some/severe dehydration
- Children with a history of recurrent wheezing
- Children enrolled in the study within the last 6 months of this visit
Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2008
Estimated Enrollment :
641 Patients enrolled
Trial Details
Trial ID
NCT00252304
Start Date
January 1 2006
End Date
July 1 2008
Last Update
October 6 2009
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Kanti Children Hospital
Kathmandu, Nepal