Status:
COMPLETED
Metabolic Effects of Chemical Interactions in Toxicity
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Oxidative Stress
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
This pilot study tests the feasibility of using GSH redox state and high resolution proton NMR spectroscopy (1H-NMR) to detect metabolic changes due to acetominophen and sulfur amino acid deficiency. ...
Detailed Description
Most occupational exposures to toxic chemicals occur in the context of complex mixtures, often in combination with varied diet, prescription drug use and disease. In principle, information-rich metabo...
Eligibility Criteria
Inclusion
- healthy volunteers males and females
Exclusion
- acute/chronic illnesses age less than 18 and greater than 40 pregnancy
Key Trial Info
Start Date :
January 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2007
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00253773
Start Date
January 1 2005
End Date
November 1 2007
Last Update
January 13 2010
Active Locations (1)
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1
Emory University Hospital
Atlanta, Georgia, United States, 30322