Status:

COMPLETED

Effect of Polymorphisms in the Adenosine a2a Receptor Gene and AMPD2 Gene on Adenosine-Induced Vasodilation and Reactive Hyperemia

Lead Sponsor:

Radboud University Medical Center

Collaborating Sponsors:

ZonMw: The Netherlands Organisation for Health Research and Development

Conditions:

Blood Flow in Healthy Volunteers

Eligibility:

All Genders

18-40 years

Phase:

NA

Brief Summary

The endogenous nucleoside adenosine can induce various cardiovascular and neurohumoral effects by stimulation of specific adenosine receptors. taken together these effects protect against ischaemia-re...

Detailed Description

The endogenous nucleoside adenosine can induce various cardiovascular and neurohumoral effects by stimulation of specific adenosine receptors. taken together these effects protect against ischaemia-re...

Eligibility Criteria

Inclusion

  • 18-40 year

Exclusion

  • hypertension
  • diabetes
  • cardiovascular or pulmonary disease
  • asthma

Key Trial Info

Start Date :

November 1 2005

Trial Type :

INTERVENTIONAL

End Date :

February 1 2006

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00253929

Start Date

November 1 2005

End Date

February 1 2006

Last Update

April 5 2007

Active Locations (1)

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Radboud University Nijmegen Medical Centre

Nijmegen, Gelderland, Netherlands, 6500HB