Status:

COMPLETED

Effect of Denileukin Diftitox on Immune System in CTCL Patients

Lead Sponsor:

University of Pittsburgh

Conditions:

Cutaneous T-cell Lymphoma

Sezary Syndrome

Eligibility:

All Genders

18+ years

Brief Summary

This is a blood and tissue study to determine the effect of the drug called denileukin diftitox on the immune system cells that may be involved in patient response to their cutaneous t-cell lymphoma. ...

Detailed Description

Although the etiology of CTCL is not fully understood, it is believed to be a malignancy proliferation of a "memory" T-cell in the context of Th2-type cytokine profile and suppressed cytotoxic T-cell ...

Eligibility Criteria

Inclusion

  • 18 and older
  • diagnosed with CTCL
  • able and willing to provide informed consent
  • will be receiving denileukin diftitox per standard guidelines

Exclusion

  • prior history of receiving Ontak
  • pregnancy

Key Trial Info

Start Date :

November 1 2005

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2007

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT00254332

Start Date

November 1 2005

End Date

September 1 2007

Last Update

March 25 2015

Active Locations (1)

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1

University of Pittsubrgh Medical Center

Pittsburgh, Pennsylvania, United States, 15213