Status:
UNKNOWN
Use of Positron Emission Tomography/Computed Tomography (PET/CT) to Assess Tumor Response to Neoadjuvant Treatment for Distal Rectal Cancer
Lead Sponsor:
University of Sao Paulo
Conditions:
Rectal Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Preoperative chemoradiation therapy is the preferred initial treatment option for distal rectal cancers. However, assessing tumor response to preoperative chemoradiation therapy remains a challenge to...
Detailed Description
Patients with distal rectal adenocarcinoma will be submitted to an initial whole body PET/CT prior to the preoperative chemoradiation therapy with 5-fluorouracil and 5040 cGy. Six weeks and 12 weeks a...
Eligibility Criteria
Inclusion
- Diagnosis of Rectal Adenocarcinoma
- Location of Tumor less than 7cm from Anal Verge
Exclusion
- Pregnancy or Nursing
- Metastatic Disease (Stage IV disease)
- Previous treatment for any cancer
- Patients clinically unable to receive neoadjuvant chemoradiotherapy
- Hypersensitivity to 18FDG
Key Trial Info
Start Date :
September 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2015
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00254683
Start Date
September 1 2005
End Date
September 1 2015
Last Update
April 14 2009
Active Locations (1)
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1
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
São Paulo, São Paulo, Brazil, 05403-010