Status:
WITHDRAWN
D-Cycloserine Augmentation of Exposure and Response Prevention Treatment for Obsessive-Compulsive Disorder
Lead Sponsor:
University of Florida
Collaborating Sponsors:
Obsessive Compulsive Foundation
Conditions:
Obsessive Compulsive Disorder
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
We propose to undertake an initial study of DCS to determine whether it has any short-term clinical benefits when added to standard ERP therapy in adults with OCD.
Detailed Description
Exposure and response prevention (ERP) has proven efficacy for OCD treatment in adults. Yet, ERP does not help all individuals, and those who benefit often remain somewhat symptomatic. Behavioral mode...
Eligibility Criteria
Inclusion
- a principal diagnosis of OCD assigned at pre-treatment, derived from the ADIS-IV, with a clinical severity rating of 4 or above;
- 18-65 years of age; and,
- an IQ of ³ 80.
Exclusion
- positive diagnosis of schizophrenia, other psychotic disorder, pervasive developmental disorder, organic brain syndrome, or mental retardation;
- do not speak English;
- are unwilling to attend twice weekly sessions; or,
- is pregnant, breast feeding a child, or attempting to become pregnant (see below rationale)
Key Trial Info
Start Date :
July 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00257361
Start Date
July 1 2005
Last Update
September 30 2013
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