Status:
COMPLETED
Comparison of Three Therapy-Based Interventions for Preventing Depression in Adolescents
Lead Sponsor:
Children's Hospital of Philadelphia
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Rutgers University
Conditions:
Depression
Eligibility:
All Genders
11-17 years
Phase:
NA
Brief Summary
This study will compare Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST), IPT-AST plus parent involvement (Enhanced IPT-AST), and Usual Care for the prevention of adolescent depression...
Detailed Description
Depression is a serious medical illness that is difficult to diagnose and treat, especially in children and adolescents. Signs of depression in children may include the following behaviors: pretending...
Eligibility Criteria
Inclusion
- Between grades 7 and 10 in school
- Score of at least 16 on the Center for Epidemiologic Studies Short Depression Scale (CES-D)
- Currently experiencing at least 2 symptoms on the K-SADS depression section, one of which is either depressed mood, irritability, or an inability to feel pleasure during normal activities
- Score of at least 61 on the Children's Global Assessment Scale (CGAS), indicating mild to moderate impairment
- English-speaking
Exclusion
- Score of 15 or less on the CES-D scale
- Currently experiencing fewer than 2 depression symptoms on the K-SADS or 2 or more symptoms on the K-SADS with no report of depressed mood, irritability, or anhedonia
- Attempted suicide or self-mutilation in the year prior to study entry
- Current active suicidal ideation and/or history of a clinically significant suicidal behavior (i.e., with intent to die and high medical lethality) or repeated patterns of self-injurious behavior
- Current major depressive disorder or dysthymia as determined by K-SADS
- Current DSM-IV diagnosis of psychosis, substance abuse or dependence, bipolar disorder, obsessive compulsive disorder, post-traumatic stress disorder, panic disorder, or conduct disorder as determined by K-SADS
- Score of 60 or less on the CGAS, indicating substantial functional impairment
Key Trial Info
Start Date :
November 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2009
Estimated Enrollment :
57 Patients enrolled
Trial Details
Trial ID
NCT00258752
Start Date
November 1 2005
End Date
June 1 2009
Last Update
October 8 2020
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Rutgers University
Piscataway, New Jersey, United States, 08554
2
New York State Psychiatric Institute
New York, New York, United States, 10032