Status:

RECRUITING

Esophageal Cancer Risk Registry

Lead Sponsor:

University of Pittsburgh

Collaborating Sponsors:

National Institutes of Health (NIH)

National Cancer Institute (NCI)

Conditions:

Esophageal Cancer

Gastroesophageal Reflux Disease (GERD)

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to identify markers in the blood and tissue that could indicate risk factors for the development and progression of esophagus cancer. This research aims to collect medical...

Detailed Description

We will enroll patients with esophageal cancer, patients who are at risk for developing esophageal cancer, and patients who have a non-cancerous esophageal disorder. All patients will be asked to fill...

Eligibility Criteria

Inclusion

  • Known or suspected esophageal or gastroesophageal junction malignancy
  • Known Barrett's metaplasia
  • Clinical management of symptomatic gastroesophageal reflux disease (GERD)
  • Achalasia
  • Hiatal hernia

Exclusion

  • Elevated pre-operative bloodwork will not have the additional biopsies taken.
  • Platelet count less than 150,000, partial thromboplastin time (PTT) of 50 or above, and/or International Normalized Ratio (INR) of 1.8 or above will not have the additional biopsies taken.

Key Trial Info

Start Date :

June 1 1999

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2050

Estimated Enrollment :

7000 Patients enrolled

Trial Details

Trial ID

NCT00260585

Start Date

June 1 1999

End Date

December 1 2050

Last Update

April 16 2025

Active Locations (1)

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1

Department of Cardiothoracic Surgery

Pittsburgh, Pennsylvania, United States, 15232