Status:
COMPLETED
Bupropion for Hospital-Based Smoking Cessation
Lead Sponsor:
University of California, San Francisco
Conditions:
Smoking
Eligibility:
All Genders
18-80 years
Phase:
PHASE3
Brief Summary
This is a randomized blinded trial of whether hospitalized smokers who are randomly assigned to receive bupropion, an antidepressant, and cognitive-behavioral counseling, are more likely to have quit ...
Detailed Description
Two hundred and seventy patients will be enrolled;approximately 135 will be randomized to each study arm over the course of 24 months. Patients will be considered smokers if they have used tobacco pro...
Eligibility Criteria
Inclusion
- currently smoking - use of tobacco products during the week prior to hospital admission and having smoked at least 5 cigarettes /day during the past year
- eligibility to receive medical care in a VA hospital
- hospitalization for at least 48 hours to provide sufficient time to identify, screen, enroll and counsel participants
- willingness to participate and give informed consent
Exclusion
- hospitalization for acute CHD syndromes
- contraindications to the use of bupropion
- family history of seizure disorder, history of severe head trauma, predisposition to seizures
- unstable psychiatric disorder
- pregnancy, lactation
- current alcohol (defined as greater than 3 drinks/day) or drug abuse (defined as current/within last 3 months use of narcotics, heroin, cocaine, amphetamines)
- current untreated depression (BDI score \> or = 30)
- terminal illness
- inability to be contacted by phone
Key Trial Info
Start Date :
July 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2007
Estimated Enrollment :
85 Patients enrolled
Trial Details
Trial ID
NCT00261170
Start Date
July 1 2003
End Date
February 1 2007
Last Update
May 23 2008
Active Locations (1)
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1
Veterans Affairs Medical Center
San Francisco, California, United States, 94121