Status:
COMPLETED
Obesity and Nonalcoholic Fatty Liver Disease
Lead Sponsor:
Washington University School of Medicine
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Non-alcoholic Fatty Liver Disease
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
The primary goal of this study is to provide a better understanding of: 1) the pathogenesis and pathophysiology of non-alcoholic fatty liver disease (NAFLD) in obese subjects, and 2) the effect of mar...
Detailed Description
Obesity is a major risk factor for non-alcoholic fatty liver disease (NAFLD), which represents a spectrum of liver diseases. NAFLD is a major health problem in the US because of its high prevalence an...
Eligibility Criteria
Inclusion
- All
- 18 - 45 years old
- Class I obesity, i.e. Body Mass Index (BMI) between 30 and 45.
- weight less than 300 lbs.
Exclusion
- Active or previous infection with hepatitis B or C, as well as other liver disease.
- History of alcohol abuse
- Diabetes
- Medications that cause liver damage or steatosis.
- Women who are pregnant or lactating.
Key Trial Info
Start Date :
October 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
51 Patients enrolled
Trial Details
Trial ID
NCT00262964
Start Date
October 1 2004
End Date
December 1 2008
Last Update
July 11 2018
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63110