Status:

COMPLETED

Metabolomic Analysis of Lung Cancer

Lead Sponsor:

University of Louisville

Collaborating Sponsors:

James Graham Brown Cancer Center

Conditions:

Carcinoma, Non-Small Cell Lung

Carcinoma, Small Cell Lung

Eligibility:

All Genders

18-75 years

Brief Summary

The purpose of this study is to learn more about the metabolic properties of lung cancer cells.

Detailed Description

It has long been known that cancer cells absorb and break down substances in the body differently than healthy, non-cancer cells. This process of absorbing and breaking down substances is known as met...

Eligibility Criteria

Inclusion

  • Lung Cancer Patients (Groups 1 \& 2)
  • patients with suspected, clinically diagnosed, or histologically diagnosed lung cancer. Occasionally, other cancers (including metastatic cancers to the lung) may be resected for the study as negative controls for NSCLC, as warranted by the particulars of the case.
  • patients must have general medical conditions to allow them to undergo surgical resection of their primary tumor

Exclusion

  • history of diabetes for the experimental group (surgery + glucose); patients with a history of diabetes are allowed in the control group (surgery/no glucose)
  • known hepatitis C or HIV (AIDS)
  • Healthy Subjects (Group 3)
  • Inclusion Criteria:
  • at least 30 years of age
  • preferably be fasting for 12 hours (minimum 8 hours) prior to enrollment

Key Trial Info

Start Date :

December 1 2005

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 24 2020

Estimated Enrollment :

249 Patients enrolled

Trial Details

Trial ID

NCT00263731

Start Date

December 1 2005

End Date

September 24 2020

Last Update

May 9 2022

Active Locations (1)

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James Graham Brown Cancer Center, University of Louisville

Louisville, Kentucky, United States, 40202