Status:
COMPLETED
D-dimer to Establish Duration of Anticoagulation After Venous Thromboembolism
Lead Sponsor:
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Conditions:
Deep Vein Thrombosis
Pulmonary Embolism
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The optimal duration of oral anticoagulant treatment in patients with idiopathic venous thromboembolism is still uncertain. The present study addresses the possible role of the D-dimer test in assessi...
Detailed Description
This is a multicenter prospective follow-up study in patients with a first episode of symptomatic idiopathic venous thromboembolism (proximal deep vein thrombosis and/or pulmonary embolism) who are tr...
Eligibility Criteria
Inclusion
- Age \> 18 years
- After a first documented idiopathic proximal deep vein thrombosis and/or pulmonary embolism
- After at least 3 months of oral anticoagulation
- After written informed consent
Exclusion
- If the Venous thromboembolism occurred:
- during pregnancy or puerperium
- after recent (i.e. within three months) fracture or plaster casting of a leg,
- after immobilization with confinement to bed for three consecutive days
- after surgery with general anesthesia lasting longer than 30 minutes
- Patients with:
- active cancer
- antiphospholipid antibody syndrome
- antithrombin deficiency
- serious liver disease or renal insufficiency (creatininemia \> 2 mg/dL),
- other indications for anticoagulation or contraindications for this treatment
- limited life expectation
- Patients who live too far from the clinical center
Key Trial Info
Start Date :
September 1 2002
Trial Type :
INTERVENTIONAL
End Date :
September 1 2005
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT00264277
Start Date
September 1 2002
End Date
September 1 2005
Last Update
March 19 2021
Active Locations (1)
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1
Dept. of Angiology & Blood Coagulation, University Hospital S. Orsola-Malpighi
Bologna, BO, Italy, 40138