Status:
COMPLETED
Bone Marrow-Derived Stem Cell Transfer in Acute Myocardial Infarctions
Lead Sponsor:
Universitaire Ziekenhuizen KU Leuven
Conditions:
Myocardial Infarction
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
Brief Summary
The benefit of reperfusion therapies for ST-elevation acute myocardial infarction (STEMI) is limited by postinfarction left ventricular (LV) dysfunction.The purpose of this study is to determine wheth...
Detailed Description
Despite early coronary reperfusion, salvage of ischemic myocardium is incomplete and loss of viable myocardium initiates a process of adverse left ventricular (LV) remodeling1, compromising clinical o...
Eligibility Criteria
Inclusion
- patients with acute myocardial infarction with cumulative ST-segment elevation \>=6mm, successful epicardial reperfusion after PCI and significant LV dysfunction
Exclusion
- patients presenting within 2 hours of symptom onset (no dilution of any treatment effect from aborted infarctions)
- patients with prior coronary artery bypass grafting, pulmonary edema, cardiogenic shock or significant co-morbidities
Key Trial Info
Start Date :
May 1 2003
Trial Type :
INTERVENTIONAL
End Date :
December 1 2005
Estimated Enrollment :
68 Patients enrolled
Trial Details
Trial ID
NCT00264316
Start Date
May 1 2003
End Date
December 1 2005
Last Update
January 17 2013
Active Locations (1)
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1
Department of Cardiology, University Hospital Gasthuisberg
Leuven, Belgium, 3000