Status:
TERMINATED
Evaluation of 2 Resection Strategies of Synchronous Colorectal Cancer Metastases
Lead Sponsor:
Rennes University Hospital
Collaborating Sponsors:
Ministry of Health, France
Conditions:
Colorectal Cancer
Hepatic Metastases
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The surgical strategy for the treatment of synchronous colorectal cancer liver metastases has not still been defined. The purpose of this study is to compare two treatment strategies in which liver re...
Detailed Description
In France, 35 000 colorectal cancers are diagnosed each year, 15 to 25% of which with hepatic metastases. It is nowadays admitted that the complete resection of these hepatic metastases represents the...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Male and female adults over 18 years old
- At least one adenocarcinoma of colon and/or rectum, histologically proven.
- No local complication at the time of surgery (no occlusion, no sub-occlusion, no massive hemorrhage, no abscesses or local invasion)
- At least one hepatic metastasis which R0 resection is possible through a conventional simple resection
- Informed written consent.
- Non inclusion criteria:
- Heart, Respiratory or Renal failure
- Physical or psychological dependence
- Chronic liver disease
- Extra-hepatic metastases
- Exclusion Criteria (at time of surgery)
- Localized or diffuse peritoneal carcinomatosis
- Non resectable lymph node metastases
- Colorectal or hepatic tumour extension towards abdominal wall and/or adjacent organ making liver R0 resection impossible immediately
- Other hepatic lesions diagnosed with ultrasound making liver R0 resection impossible immediately
Exclusion
Key Trial Info
Start Date :
March 2 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 11 2017
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT00264979
Start Date
March 2 2006
End Date
December 11 2017
Last Update
March 11 2019
Active Locations (14)
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1
Chirurgie générale viscérale et digestive - Hôpital Nord
Amiens, France, 80080
2
Service de Chirurgie viscérale, digestive et cancérologie - Hôpital Jean Mingoz
Besançon, France, 25000
3
Chirurgie digestive, thoracique et cancérologie
Dijon, France, 21000
4
Département de Chirurgie - CRLCC Léon Bérard
Lyon, France, 69008