Status:
COMPLETED
Right Ventricular Failure in Congenital Heart Defects
Lead Sponsor:
Competence Network for Congenital Heart Defects
Collaborating Sponsors:
German Federal Ministry of Education and Research
Conditions:
Heart Failure
Congenital Heart Defects
Eligibility:
All Genders
14+ years
Brief Summary
Usually, "heart failure" refers to myocardial insufficiency of the left ventricle. However, in patients with congenital heart defects, often predominantly the right ventricle is affected. Brain natri...
Detailed Description
Usually, "heart failure" refers to myocardial insufficiency of the left ventricle. In patients with congenital heart defects, predominantly the right ventricle and secondarily the right atrium and the...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Patient group:
- Adolescents (at least14 years old)/adults with a surgically treated congenital heart defect that leads to stress of the right ventricle
- Consent of the patient, in the case of minors additional consent of the parents or the legal representative, to participation in the study.
- Control group:
- Healthy population, comparable to the patient sample with respect to age and gender
- No heart defect, normal echocardiogram, ECG and MRI
- Consent of the test person, in case of minors additional consent of the parents or the legal representative, to participation
- Exclusion Criteria
- Other clinically significant illnesses (e.g. malignant disease, impaired thyroid function)
- Morphological right ventricle as systemic ventricle
- Haemodynamically relevant left ventricular failure
- Treatment with a beta blocker
Exclusion
Key Trial Info
Start Date :
June 1 2003
Trial Type :
OBSERVATIONAL
End Date :
July 1 2006
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT00266201
Start Date
June 1 2003
End Date
July 1 2006
Last Update
August 18 2011
Active Locations (9)
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1
Zentrum fuer Kinderheilkunde und Jugendmedizin
Freiburg im Breisgau, Baden-Wurttemberg, Germany, D-79106
2
Kinderherzzentrum des Klinikum Stuttgart
Stuttgart, Baden-Wurttemberg, Germany, D-70176
3
Universitätsklinikum Tuebingen
Tübingen, Baden-Wurttemberg, Germany, D-72076
4
Herzzentrum Hamburg, UKE
Hamburg, Hamburg, Germany, D-29246