Status:
COMPLETED
Physical Activity, Insulin Resistance and Function of Fat Tissue in the Offspring of Patients With Type 2 Diabetes
Lead Sponsor:
NHS Greater Glasgow and Clyde
Collaborating Sponsors:
British Heart Foundation
Conditions:
Type 2 Diabetes Mellitus
Cardiovascular Diseases
Eligibility:
FEMALE
20-45 years
Phase:
NA
Brief Summary
Offspring of patients with type 2 diabetes have increased risk of developing diabetes and are typically more insulin resistant than their peers with no diabetes family history. We have recently demons...
Eligibility Criteria
Inclusion
- 2 subject groups - 'control' and 'offspring'
- Offspring - at least 1 parent diagnosed with type 2 diabetes before age 65
- Controls - no history of type 2 diabetes in 1st or 2nd degree relatives
- In generally good health
- Non-smoker
- Fasting glucose \< 7 mmol/l
- Blood pressure \<160/90 mm Hg
- No established CHD (e.g. MI, stroke, CABG, PCTA)
Exclusion
- Established CHD (e.g. MI, stroke, CABG, PCTA)
- diabetes
- smoking
- hypertension (BP \> 160/90 mmHg)
- pregnancy
Key Trial Info
Start Date :
September 1 2004
Trial Type :
INTERVENTIONAL
End Date :
February 1 2007
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00268541
Start Date
September 1 2004
End Date
February 1 2007
Last Update
April 20 2007
Active Locations (1)
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1
University of Glasgow
Glasgow, United Kingdom, G12 8QQ