Status:
COMPLETED
Topical Vitamin A Versus Vehicle Cream in the Treatment of Aged Skin
Lead Sponsor:
University of Michigan
Conditions:
Skin Aging
Purpura
Eligibility:
All Genders
70+ years
Phase:
PHASE2
Brief Summary
The objectives of this study are to evaluate the safety and efficacy of 0.5% retinol (Vitamin A) versus it's vehicle cream in the treatment and prevention of skin aging and Bateman's Purpura (bruising...
Detailed Description
Human skin becomes thinner and looses its elasticity with increasing age. These features of intrinsic skin aging are due to reduction in collagen synthesis with a concomitant increase in collagen and ...
Eligibility Criteria
Inclusion
- Male and female
- 70 years of age or older
- history of Bateman's purpura on arms
- Relatively good general health and able to perform daily tasks
Exclusion
- Sensitivity to any formulation ingredients
- History of Cardiovascular disease with continuing deficits (example: partial paralysis)
- Participated in any clinical trials within last 30 days
- Topical steroids or other drugs two weeks prior to study entry (short-term application of topical antimicrobials is allowed)
- Hormone replacement therapy within last 6 months.
Key Trial Info
Start Date :
September 1 2000
Trial Type :
INTERVENTIONAL
End Date :
February 1 2002
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00272610
Start Date
September 1 2000
End Date
February 1 2002
Last Update
June 24 2015
Active Locations (1)
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1
University of Michigan
Ann Arbor, Michigan, United States, 48109