Status:

COMPLETED

Comparing Two Instrumentation Systems for the Treatment of Adolescent Scoliosis

Lead Sponsor:

The Hospital for Sick Children

Collaborating Sponsors:

Canadian Institutes of Health Research (CIHR)

Synthes Canada

Conditions:

Scoliosis

Eligibility:

All Genders

8-18 years

Phase:

PHASE2

Brief Summary

Idiopathic scoliosis affects 2-5% of adolescents. This study will compare the quality of life, functional outcome, cosmetic result, and the correction of spinal deformity of two instrumentation system...

Eligibility Criteria

Inclusion

  • Age 8-18 years
  • Diagnosis of idiopathic scoliosis requiring posterior instrumentation and fusion(including those also requiring anterior release with or without anterior instrumentation) who could receive either the USS or the Moss Miami system
  • Patients with scoliosis and an incidental finding of conus \< L1-2 disc level, provided they have no symptoms or signs
  • Patients with scoliosis and an incidental finding of a small syrinx (provided the syrinx is non-progressive and does not require neurosurgical treatment)
  • Patients with non-progressive spondylolysis

Exclusion

  • Spinal cord abnormalities with any neurologic symptoms or signs
  • Spinal cord lesions requiring neurosurgical interventions, such as hydromyelia requiring Arnold Chiari decompression
  • Primary muscle diseases, such as muscular dystrophy
  • Neurologic diseases (e.g. Charcot-Marie Tooth, Guillain-Barre syndrome, cerebral palsy, or spina bifida, etc.)
  • Primary abnormalities of bones(e.g. osteogenesis imperfecta)
  • Congenital scoliosis

Key Trial Info

Start Date :

September 1 1997

Trial Type :

INTERVENTIONAL

End Date :

September 1 2002

Estimated Enrollment :

126 Patients enrolled

Trial Details

Trial ID

NCT00273598

Start Date

September 1 1997

End Date

September 1 2002

Last Update

October 12 2017

Active Locations (1)

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1

The Hospital for Sick Children

Toronto, Ontario, Canada, M5G 1X8