Status:
SUSPENDED
Effect of Garlic on Inflammatory Mediators
Lead Sponsor:
Albany Medical College
Conditions:
Healthy
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This research will investigate the effect of garlic oil extract when added to daily diet on inflammatory mediators and blood clotting activation.
Detailed Description
To investigate the pharmacokinetics of one of the garlic oil macerate, Ajoene, the anti-inflammatory effect of garlic oil macerate on the pro-inflammatory transcription factor NF-kB, it's activating p...
Eligibility Criteria
Inclusion
- 18 years of age and older
- Normal subjects with BMI \<25, obese subjects with BMI \>30
- Subjects who have consented to adhere to the diet, regular weekly visits, and blood draws.
Exclusion
- Subjects on any antioxidant medication.
- Patient on non-steroidal anti-inflammatory drug.
- On any agent with antioxidant properties.
- History of drug or alcohol abuse.
- Any life threatening disease.
- On any agent with significant antioxidant properties.
- Taking garlic extracts in the diet regularly.
Key Trial Info
Start Date :
April 1 2006
Trial Type :
INTERVENTIONAL
End Date :
March 1 2007
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT00275405
Start Date
April 1 2006
End Date
March 1 2007
Last Update
March 20 2007
Active Locations (1)
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1
Albany Medical Center
Albany, New York, United States, 12208