Status:

COMPLETED

The Effects of Angiotensin II Receptor Blockade on Kidney Function and Scarring After Liver Transplant

Lead Sponsor:

Mayo Clinic

Conditions:

Liver Transplant Recipients

Eligibility:

All Genders

18-70 years

Phase:

PHASE4

Brief Summary

This research study is being done to study the effects, both good and bad, of calcineurin inhibitors and the drug Cozaar (losartan), on kidney function and kidney scarring following a liver transplant...

Detailed Description

This study is a double-blinded, placebo controlled trial to help determine the pathogenesis of chronic renal dysfunction in patients undergoing liver transplantation. It will examine the renal functio...

Eligibility Criteria

Inclusion

  • Participants who will be undergoing a liver transplant and are between the ages of 18 to 70 years of age.

Exclusion

    Key Trial Info

    Start Date :

    December 1 2004

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    August 1 2007

    Estimated Enrollment :

    62 Patients enrolled

    Trial Details

    Trial ID

    NCT00275639

    Start Date

    December 1 2004

    End Date

    August 1 2007

    Last Update

    January 6 2012

    Active Locations (1)

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    Mayo Clinic

    Rochester, Minnesota, United States, 55905