Status:
COMPLETED
The Effect of High Dose Simvastatine on Multiple Myeloma
Lead Sponsor:
Vejle Hospital
Conditions:
Multiple Myeloma
Eligibility:
All Genders
18+ years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of the study is to evaluate the effect of high doses of Simvastatine on bone metabolisme and biochemical markers of disease in Multiple Myeloma
Eligibility Criteria
Inclusion
- multiple myeloma-patients in need of treatment
- stable og progressive disease
- age = or \> 18 years
- performance status \< 3
- life expectancy \> 3 months
Exclusion
- pregnancy
- patients incapable of giving personally concent
- renal insufficiens with creatinine clearance below 25 ml/min
- alanin aminotransferasis \> 2,5 x upper reference limit
- thyroxine below lower reference limit
- known familiar muscle-disease ar previous myopati
- creatinine kinase \> 10 x upper reference limit
- medication with drugs with known interactions wiht simvastatine
Key Trial Info
Start Date :
February 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2007
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00281476
Start Date
February 1 2006
End Date
November 1 2007
Last Update
November 1 2011
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