Status:

COMPLETED

Effect of the Dietary Supplement SAMe on Blood Homocysteine Levels

Lead Sponsor:

Mayo Clinic

Conditions:

Heart Disease

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The purpose of this study is to determine if the oral intake of the dietary supplement SAMe increases blood homocysteine levels in healthy human subjects.

Detailed Description

S-adenosyl-L-methionine (SAMe or AdoMet) is a commonly used nutritional supplement available in the United States since 1999. SAMe is metabolized to homocysteine, a known cardiovascular risk factor. N...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Women and men age 18 - 65
  • Able to understand and sign a consent form
  • Exclusion criteria:
  • Smoking
  • Pregnant or lactating
  • Women actively trying to conceive
  • Diagnosis of panic disorder or bipolar disorder

Exclusion

    Key Trial Info

    Start Date :

    June 1 2005

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    May 1 2006

    Estimated Enrollment :

    52 Patients enrolled

    Trial Details

    Trial ID

    NCT00284011

    Start Date

    June 1 2005

    End Date

    May 1 2006

    Last Update

    January 6 2012

    Active Locations (1)

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    Mayo Clinic

    Rochester, Minnesota, United States, 55905