Status:

COMPLETED

GLP-1 Infusion and Long-Time Fasting

Lead Sponsor:

University of Aarhus

Conditions:

Type 2 Diabetes

Eligibility:

MALE

20-50 years

Phase:

NA

Brief Summary

GLP-1 is an incretin hormone that simulates insulin secretion and inhibits glucagon secretion in a glucose dependent way. Below normal plasma glucose levels the effects of GLP-1 stop and the risk of h...

Detailed Description

GLP-1 is an incretin hormone that simulates insulin secretion and inhibits glucagon secretion dependent on a normal plasma glucose.It also inhibits gastric emptying and has a trophic effect on the pan...

Eligibility Criteria

Inclusion

  • healthy male, age 20-50 years, BMI 20-30 kg/m2, Blood pressure \< 140/90 mmHg, caucasian.

Exclusion

  • Diabetes in relatives, anaemia, any significant disease, smoking.

Key Trial Info

Start Date :

December 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2007

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT00285896

Start Date

December 1 2005

End Date

May 1 2007

Last Update

July 11 2008

Active Locations (1)

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1

Department of pharmacology, Aarhus university and Medical department M, Aarhus University hospital

Aarhus, Denmark, 8000