Status:
COMPLETED
Markers in Exhaled Breath Condensate in Obstructive Sleep Apnoea (OSA) Patients
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Obstructive Sleep Apnea
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Patients with obstructive sleep apnoea (OSA) have repetitive episodes of partial or complete upper airway obstruction during sleep. This leads to sleep fragmentation and symptoms like excessive daytim...
Detailed Description
Measurement of exhaled Nitric Oxide and collection of exhaled breath condensate and peripheral blood. This will be done 2 to 4 times(on admission,the morning after sleep study,immediately after CPAP t...
Eligibility Criteria
Inclusion
- Patients will be recruited upon admission for sleep study under the Division of Respiratory Medicine, Prince of Wales Hospital.
- Patients who are aged 18 to 60 will be recruited.
Exclusion
- Known history of respiratory disease that will affect inflammatory markers in EBC like asthma, chronic obstructive pulmonary disease and bronchiectasis.
- Upper or lower respiratory tract infection within 6 weeks from the study.
- Current smokers, or ex-smoker who quitted for less than a year.
- Pregnant subjects.
- Any form of malignancies or serious medical illness that will affect the survival of the subject significantly in 1 year period.
Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2010
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00287638
Start Date
January 1 2006
End Date
January 1 2010
Last Update
January 22 2010
Active Locations (1)
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1
Prince of Wales Hospital
Shatin, N.T., Hong Kong, 000