Status:
RECRUITING
Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma
Lead Sponsor:
Case Western Reserve University
Collaborating Sponsors:
University Hospitals Cleveland Medical Center
Washington University School of Medicine
Conditions:
Barrett's Esophagus
Esophageal Neoplasm
Eligibility:
All Genders
18+ years
Brief Summary
The overall objectives of this BETRNet Research Center (RC) are: 1. to conduct a rigorous, integrated spectrum of transdisciplinary human research in Barrett's esophagus (BE) and esophageal adenocarc...
Detailed Description
This research will eventually lead to the identification of inherited genetic changes that cause Barrett's esophagus and esophageal cancer. It will help the investigators develop better methods for pr...
Eligibility Criteria
Inclusion
- Eligible cases will be defined as those patients and their family members who meet the following criteria:
- Barrett's esophagus confirmed by review of pathology and endoscopy report or adenocarcinoma of the esophagus or family members of person with Barrett's esophagus or adenocarcinoma of the esophagus.
- Male or female age 18 or older at time of enrollment or male or female less than 18 years of age at time of enrollment with parental consent.
- Ability to give informed consent, if patient is age 18 or older.
Exclusion
Key Trial Info
Start Date :
October 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 31 2028
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT00288119
Start Date
October 1 2005
End Date
July 31 2028
Last Update
July 18 2025
Active Locations (10)
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1
Johns Hopkins Hospital
Baltimore, Maryland, United States, 21205
2
Mayo Clinic
Rochester, Minnesota, United States, 55905
3
Washington University School of Medicine
St Louis, Missouri, United States, 63110
4
Columbia University Medical Center
New York, New York, United States, 10032