Status:
COMPLETED
The Effect of Positive Airway Pressure on Heart Rate Variability
Lead Sponsor:
Christiana Care Health Services
Conditions:
Obstructive Sleep Apnea
Eligibility:
All Genders
18-75 years
Brief Summary
This study is designed to determine the effect of continuous positive airway pressure (CPAP) or bi-level positive airway pressure (BiPAP) on heart rate variability (HRV) in patients with obstructive s...
Detailed Description
Visit 1: You will come to the Diabetes and Metabolic Research Center having refrained from taking your routine medications and having not eaten in the last 8 hours, avoided using caffeine-containing b...
Eligibility Criteria
Inclusion
- Individuals aged 18-75 years old.
- Individuals with diagnosed OSA.
Exclusion
- 1\. Individuals who are receiving treatment for OSA, excluding those being treated by weight loss.
- 2\. Individuals who have had pharyngeal surgery (i.e., uvulopalatopharyngoplasty).
- 3\. Individuals who have arterial oxygen desaturation episodes or apneic episodes not felt to be due to OSA.
- 4\. Individuals whose treatment dosage changes 2 months prior to, or during, the study for antihypertensive and antidiabetic medications and the following medications that may affect the autonomic nervous system: anti-tuberculosis drugs, nitrofurantoin, metronidazole, chloramphenicol, perhexiline maleate, cordarone, clofibrate, tricyclic antidepressants, phenytoin, barbiturates, neuroleptic drugs, antiparkinsonism drugs, and nitrated drugs.
Key Trial Info
Start Date :
July 1 2003
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2008
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT00289666
Start Date
July 1 2003
End Date
September 1 2008
Last Update
July 11 2016
Active Locations (1)
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1
Christiana Care Health Service
Newark, Delaware, United States, 19713