Status:
COMPLETED
Real Time Assessment of Drug Craving, Use, and Abstinence During Outpatient: A Development and Feasibility Study
Lead Sponsor:
National Institute on Drug Abuse (NIDA)
Conditions:
Cocaine Addiction
Opiate Addiction
Eligibility:
All Genders
18-65 years
Brief Summary
Background: * The treatment of addiction often hinges on preventing relapse into drug-using behaviors, which occurs at high rates even after prolonged abstinence. Research has shown that constant rep...
Detailed Description
Background. We have already completed the original, major arm of this protocol (a natural-history study of craving and lapse). Still open for enrollment is the second minor arm (a within-subject trial...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Age between 18 and 65;
- Evidence of physical dependence on opioids (self-report and physical exam);
- Evidence of cocaine and opiate use (self-report and urine screen).
- \<TAB\>
- EXCLUSION CRITERIA:
- Schizophrenia or any other DSM-IV psychotic disorder; history of bipolar disorder; current Major Depressive Disorder;
- Current dependence on alcohol or sedative-hypnotic, e.g. benzodiazepine (by DSM-IV criteria);
- Cognitive impairment severe enough to preclude informed consent or valid self-report;
- Medical illness that in the view of the investigators would compromise participation in research;
- Urologic conditions that would inhibit urine collection;
- In arm 2 only: current or recent maintenance on a methadone dose substantially higher than the arm 2 ceiling dose of 100 mg/day; the MRP will evaluate this case by case.
Exclusion
Key Trial Info
Start Date :
August 15 2003
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 11 2013
Estimated Enrollment :
230 Patients enrolled
Trial Details
Trial ID
NCT00292136
Start Date
August 15 2003
End Date
June 11 2013
Last Update
April 5 2018
Active Locations (1)
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1
National Institute on Drug Abuse
Baltimore, Maryland, United States, 21224