Status:
COMPLETED
Cognitive Remediation for Schizophrenia
Lead Sponsor:
University of Maryland, Baltimore
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
VISN 5 Mental Illness Research, Education and Clinical Center
Conditions:
Schizophrenia
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the efficacy of an innovative, computer driven cognitive rehabilitation program for individuals with schizophrenia and related disorders.
Detailed Description
Schizophrenia is associated with neurocognitive impairment, diminished life satisfaction, lack of independence, and poor functioning in social, occupational and other desired and expected community ro...
Eligibility Criteria
Inclusion
- Diagnosis of either schizophrenia or schizoaffective disorder according to DSM-IV criteria
- Age 18 through 50
- Subjects will be clinically stable as judged by current outpatient or inpatient treatment staff
- Primary psychiatric medication is a new generation antipsychotic other than Clozapine and/or a dose of first generation antipsychotic equivalent to 10 mg. of less of haloperidol for one month prior to enrollment.
Exclusion
- Documented history of organic brain disease
- Documented history of mental retardation
- Physical limitations (e.g., with hearing or vision) that would interfere substantially with use of computer-based exercises
- Diagnosis of current Substance Dependence according to DSM-IV criteria
- Participation in the prior full trial of this remediation program (this exclusion is meant to apply to individuals participating in the full controlled trial, and not to individuals participating in the preliminary sub-study).
Key Trial Info
Start Date :
November 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2007
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00295048
Start Date
November 1 2004
End Date
May 1 2007
Last Update
July 21 2021
Active Locations (3)
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1
University of Maryland - Walter P. Carter Center
Baltimore, Maryland, United States, 21201
2
VA Maryland Health Care Systen
Baltimore, Maryland, United States, 21201
3
MOSAIC Community Services
Catonsville, Maryland, United States, 21228