Status:

UNKNOWN

CYA Versus MMF for Treatment of Moderate-Severe Psoriasis.

Lead Sponsor:

University Hospital Muenster

Collaborating Sponsors:

Hoffmann-La Roche

Conditions:

Psoriasis

Eligibility:

All Genders

18-75 years

Phase:

PHASE2

Brief Summary

Psoriasis is an immuno-mediated skin disorder, which affects about 2-3% of the population worldwide. For moderate-severe forms of psoriasis systemic immunosuppression is the treatment of choice. This ...

Detailed Description

Not needed.

Eligibility Criteria

Inclusion

  • moderate-to-severe psoriasis (PASI Score equal and greated 10)
  • written informed consent
  • for female patients effective birth control

Exclusion

  • psoriasis arthritis
  • psoriasis palmo-plantaris
  • erythrodermic psoriasis
  • drug-induced psoriasis
  • pregnancy
  • previous treatment with cyclosporine A or mycophenolate mofetil
  • pregnancy
  • reduced liver function
  • high blood pressure
  • reduced kidney function
  • severe viral or bacterial infection
  • 2 weeks before or after vaccinations
  • innate or acquired immunodeficiency
  • severe neurologic or psychiatric symptoms
  • participation in other trials
  • other reasons voiced by the treating physician

Key Trial Info

Start Date :

May 1 2000

Trial Type :

INTERVENTIONAL

End Date :

October 1 2006

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00295425

Start Date

May 1 2000

End Date

October 1 2006

Last Update

October 5 2006

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Nicolas Hunzelmann

Cologne, Germany

2

Prof. Michael Sticherling

Leipzig, Germany