Status:

COMPLETED

A Study of the Safety and Effectiveness of Galantamine Hydrobromide in Patients With Alzheimer's Disease

Lead Sponsor:

Janssen Cilag Pharmaceutica S.A.C.I., Greece

Conditions:

Alzheimer Disease

Eligibility:

All Genders

Brief Summary

The purpose of this study is to evaluate the safety and effectiveness of galantamine hydrobromide in patients with Alzheimer's disease who have not received or have not responded to treatment with med...

Detailed Description

Galantamine hydrobromide is a medication that is approved for the treatment of symptoms of Alzheimer's disease. In accordance with international guidelines, studies are conducted after a drug is marke...

Eligibility Criteria

Inclusion

  • Patients with a score of 10-26 on the Mini Mental Status Exam
  • Patients who have not yet received treatment for their Alzheimer's disease with a medication similar to galantamine or patients who have been treated with as medication similar to galantamine hydrobromide and who have discontinued that medication due to lack of effectiveness or poor tolerability (adverse events)

Exclusion

  • Patients with severely decreased liver or kidney function
  • Patients with a digestive system or urinary blockage who are recovering from digestive system or urinary bladder surgery
  • Patients with clinically significant unstable or uncontrolled hormonal or mental disease
  • Patients who are unable to take the medication either alone or with help from another person who is available during the entire study period

Key Trial Info

Start Date :

June 1 2004

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2005

Estimated Enrollment :

344 Patients enrolled

Trial Details

Trial ID

NCT00297362

Start Date

June 1 2004

End Date

October 1 2005

Last Update

March 26 2012

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