Status:
COMPLETED
Gradual vs. Abrupt Cessation Treatment for Smoking
Lead Sponsor:
University of Vermont
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Smoking Cessation
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
This study tests whether stopping smoking by gradually cutting down first is more or less successful than stopping abruptly. We hypothesize that stopping by gradually cutting down first will produce m...
Detailed Description
For cigarette smokers who intend to stop smoking, most treatment guidelines recommend abrupt cessation. There is evidence from some small studies that gradually reducing the number of cigarettes per d...
Eligibility Criteria
Inclusion
- Interested in quitting gradually
- At least 18 years old
- Daily cigarette smoker
- Smoke at least 15 cigarettes per day (CPD)
- No change greater than 20% in CPD in the last month
- Interested in quitting in next 30 days
- Must agree to not use non-cigarette tobacco during study
- No use of smoking cessation medication in last month
- Have phone with voice mail
- Willing to use nicotine lozenge
- No other person in household in study
- Fluent/literate in English
Exclusion
- Women who are pregnant or breastfeeding
- Currently using medication for depression or asthma
- Heart disease requiring medication
- Heart attack in last month
- Irregular heartbeat
- High blood pressure not controlled by medication
- Stomach ulcers
- Diabetes
Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2008
Estimated Enrollment :
750 Patients enrolled
Trial Details
Trial ID
NCT00297492
Start Date
January 1 2006
End Date
February 1 2008
Last Update
September 20 2013
Active Locations (1)
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1
University of Vermont Human Behavioral Pharmacology Lab
Burlington, Vermont, United States, 05401