Status:
COMPLETED
Molecular Associations With Reproductive Failure
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
Crown Family Philanthropies
Conditions:
Spontaneous Abortions
Infertility
Eligibility:
FEMALE
18-45 years
Brief Summary
The overall hypothesis to be tested is: women with the molecular phenotype of highly skewed X chromosome inactivation are at increased risk of spontaneous abortion.
Detailed Description
The overall hypothesis to be tested is: women with the molecular phenotype of highly skewed X chromosome inactivation are at increased risk of spontaneous abortion. We will investigate this hypothesi...
Eligibility Criteria
Inclusion
- Patients are prospectively ascertained women with either a new pregnancy (specific aim 1), or a spontaneous abortion (specific aim 2).
- Given our enrollment strategy, we anticipate enrolling women between the ages of 18 and 45.
Exclusion
- The study is limited only to females.
- Children are not eligible to participate in this study. Because the patient populations studied are (aim 1) women with primary infertility undergoing fertility treatment and (aim 2) women who have recently had a spontaneous abortion, the research topic is irrelevant to children.
Key Trial Info
Start Date :
September 1 2000
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2008
Estimated Enrollment :
475 Patients enrolled
Trial Details
Trial ID
NCT00298116
Start Date
September 1 2000
End Date
January 1 2008
Last Update
December 8 2014
Active Locations (1)
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1
Magee-Womens Hospital
Pittsburgh, Pennsylvania, United States, 15213