Status:

WITHDRAWN

Urinary Aquaporine 2 in Patients With Syndrome of Inappropriate ADH-secretion Caused by Treatment With Antiepileptic Medicine

Lead Sponsor:

Regional Hospital Holstebro

Conditions:

Syndrome of Inappropriate ADH-secretion

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Patients treated with the antiepileptic drug Oxcarbazepine often develop syndrome of inappropriate secretion of antidiuretic hormone(SIADH)We want to test the hypothesis, that these patients have a hi...

Detailed Description

The purpose of the study is to determine the amount of Aquaporine2(AQP2)in the urine in patients treated with the antiepileptic drug Oxcarbazepine before and after the administration of fluid restrict...

Eligibility Criteria

Inclusion

  • Age more than 18 years, both men and women, patients with epilepsia treated with Oxcarbazepine, and a Sodium content in plasma lower than 130 mmol/liter

Exclusion

  • severe diseases in the heart, lungs or liver;diabetes mellitus, other not-well treated diseases in endocrine organs, cancer; unwillingness to participate

Key Trial Info

Start Date :

May 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00298753

Start Date

May 1 2005

Last Update

September 15 2015

Active Locations (1)

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1

Department of Medicine, Holstebro Hospital

Holstebro, Jutland, Denmark, 7500