Status:
COMPLETED
Genetic and Physical Characteristics of Rett Syndrome
Lead Sponsor:
University of Alabama at Birmingham
Collaborating Sponsors:
Rare Diseases Clinical Research Network
Greenwood Genetic Center
Conditions:
Rett Syndrome
MECP2 Duplication Disorder
Eligibility:
All Genders
Brief Summary
Rett Syndrome (RTT) is a genetic brain disorder that occurs almost exclusively in females and is usually caused by a change (mutation) in the gene MECP2. The disorder is characterized by multiple deve...
Detailed Description
RTT is a brain disorder that causes problems with childhood development. It is usually caused by an abnormality (mutation) in the gene MECP2. RTT can cause severe impairments in movement and communica...
Eligibility Criteria
Inclusion
- Meets clinical criteria for classic or variant RTT or tests positive for an MECP2 gene mutation or a MECP2 duplication or a mutation in CDKL5 or FOXG1.
Exclusion
- Unwilling or unable to travel to study sites for annual or biannual evaluations
Key Trial Info
Start Date :
March 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2015
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00299312
Start Date
March 1 2006
End Date
October 1 2015
Last Update
March 16 2017
Active Locations (11)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
2
Children's Hospital of Oakland
Oakland, California, United States, 94709
3
University of California San Diego
San Diego, California, United States, 92123
4
University of Colorado Denver
Denver, Colorado, United States, 80045-2571