Status:
COMPLETED
MIDCAB Versus DES in Proximal LAD Lesions
Lead Sponsor:
University of Leipzig
Collaborating Sponsors:
Cordis Medizinische Apparate GmbH
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
18-100 years
Phase:
NA
Brief Summary
Percutaneous coronary intervention with a sirolimus-coated stent compared to minimally invasive bypass surgery in patients with isolated proximal left anterior descending coronary arteries in terms of...
Eligibility Criteria
Inclusion
- Single-vessel disease of the proximal LAD with a stenosis \> 50% (multivessel disease only if further coronary vessel stenoses do not require treatment)
- Patients with angina pectoris (CCS 1-4)
- Asymptomatic patients if clear signs of ischemia in the segments supplied by the LAD as assessed by bicycle ergometry or treadmill and/or scintigraphically and/or stress echo
- Patients for whom both methods of treatment are equally possible
- Consensus between the cardiac surgeon and the cardiologist that both inclusion and exclusion criteria are met in the selected case
- Informed consent of the patient.
Exclusion
- Patients \< 18 years
- Pregnancy
- Previous coronary artery bypass surgery
- Concomitant diseases that lead to a greater risk for each of the treatment strategies
- Significant peripheral arterial occlusive disease
- Concomitant disease with limited life expectancy (e.g. malignant tumours that have not been curatively treated)
- Objective follow-up examination not possible due to physical or mental handicap
- Participation in another study.
- Angiographical exclusion criteria:
- Left main stem stenosis
- Multivessel disease for which surgical or interventional therapy on other vessel areas is required.
- Diagonal/septal branch \> 1.5 mm, which might be compromised by a stent
- Need for acute intervention (e.g. acute myocardial infarction)
- Total occlusion of the LAD
Key Trial Info
Start Date :
January 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2008
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT00299429
Start Date
January 1 2003
End Date
July 1 2008
Last Update
June 26 2018
Active Locations (1)
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1
University of Leipzig - Heart Center
Leipzig, Germany, 04289